Mycon-soft lenses (made by Tokyo contact lens Co., Japan) were contaminated experimentally with coagulase positive staphylococcus aureus and pseudomonas aeruginosa and sterilizing effects of some disinfectants (3% H_20_2, 6% H_20_2, 0.1% Benzalkonium and 1 : 1000 Merthiolate solutions) on those contaminated lenses were studied. .
The following results were obtained:
1. SCL contaminaetd with staphylcoccus were sterilized by soaking in 3% H_20_2, 6% H_20_2, or 1:1000 Merthiolate solution over 15 minutes, and in 0. 1 Benzalkonium over 60 minutes.
2. SCL contaminated with pseudomonas aeruginosa were sterilized by soaking in 6% H_20_2 over 15 minutes, in 1 : 1000 Merthiolate solution over 60 minutes, in 3% H_20_2 over 60 minutes, but no sterilization was obtained by soaking in 0.1% Benzalkonium solution for less than 180 minutes.
3. No signs of irritation were noted on rabbit corneas fitted with SCL after soaking in 3% H_202 or 6% H_20_2 for 15 minutes followed by soaking in 20cc of normal saline for 15 minutes.
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